Description

3'-Bromo-[1,1'-Biphenyl]-4-Carbonitrile is a high-purity biphenyl derivative featuring both bromo and cyano functional groups, making it a versatile and valuable synthetic intermediate. This compound is critical for facilitating complex coupling reactions and serving as a key precursor in advanced material synthesis. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and organic electronics sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in creating complex biaryl structures common in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its halogen and nitrile groups for further functionalization.
• Material Science Research: Acts as a precursor for organic semiconductors, liquid crystals, and other advanced organic electronic materials due to its rigid biphenyl core.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct more complex molecular architectures.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new synthetic pathways.

Basic Information

Product Name	3'-Bromo-[1,1'-Biphenyl]-4-Carbonitrile
CAS No.	160521-46-0
Molecular Formula	C13H8BrN
Molecular Weight	258.11 g/mol
Synonyms	[1,1'-Biphenyl]-4-carbonitrile, 3'-bromo-; 3'-Bromobiphenyl-4-carbonitrile; 4-Cyano-3'-bromobiphenyl; 3-Bromo-4-cyanobiphenyl; (3'-Bromo[1,1'-biphenyl]-4-yl)carbonitrile; 3'-Bromo-4-cyanobiphenyl; 4'-Bromo-4-cyanobiphenyl (common numbering variation); Biphenyl-4-carbonitrile, 3'-bromo- derivative
EINECS	Contact for details

Quality Control

Our 3'-Bromo-[1,1'-Biphenyl]-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.