Description

n-Boc-5-Oxo-Dl-Proline is a protected amino acid derivative of significant synthetic utility. This compound serves as a versatile building block in organic synthesis, particularly for the preparation of complex peptides and peptidomimetics. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs.
• Peptide Chemistry: Used as a protected proline analog for the solid-phase and solution-phase synthesis of modified peptides.
• Protease Inhibitor Development: Acts as a core scaffold in the research and development of enzyme inhibitors targeting proteases.
• Chemical Biology Research: Employed in the study of protein structure and function, and in the creation of molecular probes.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in catalytic asymmetric reactions to introduce chirality.
• Academic & Industrial R&D: Serves as a fundamental reagent in organic chemistry laboratories for method development and novel compound library generation.

Basic Information

Product Name	n-Boc-5-Oxo-Dl-Proline
CAS No.	160401-16-1
Molecular Formula	C₁₀H₁₅NO₅
Molecular Weight	229.23 g/mol
Synonyms	5-Oxo-DL-proline, 1-(1,1-Dimethylethyl) ester; 1-tert-Butyl 2-(5-oxopyrrolidine-2-carboxylate); Boc-5-oxo-DL-proline; (RS)-1-(tert-Butoxycarbonyl)-5-oxopyrrolidine-2-carboxylic acid; DL-1-Boc-5-oxoproline; tert-Butyl 5-oxo-DL-prolinate; 5-Oxoproline, 1-(1,1-dimethylethyl) ester, DL-
EINECS	Contact for details

Quality Control

Our n-Boc-5-Oxo-Dl-Proline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.