Description

Sp-8-Pcpt-Cgmps Sodium Salt is a high-purity biochemical reagent used in advanced research and development. This compound is critical for modulating specific intracellular signaling pathways, particularly those involving cyclic nucleotides. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in drug discovery and molecular biology studies.

Application

• Biochemical Research: As a potent and selective activator of cyclic GMP-dependent protein kinase (PKG) for studying cardiovascular and neurological signal transduction.
• Drug Discovery: A key tool compound in high-throughput screening assays to identify novel therapeutics targeting PKG pathways.
• Cellular Physiology Studies: Used to investigate smooth muscle relaxation, platelet function, and neuronal plasticity mechanisms.
• Enzyme Kinetics: Serves as a substrate analog in enzymatic studies to understand PKG specificity and regulation.
• Reference Standard: Employed as an analytical standard in quality control for related pharmaceutical intermediates.

Basic Information

Product Name	Sp-8-Pcpt-Cgmps Sodium Salt
CAS No.	160385-87-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	8-(4-Chlorophenylthio)guanosine-3',5'-cyclic monophosphorothioate, Sp-8-pCPT-cGMPS sodium salt; Sp-8-(4-Chlorophenylthio)-cGMPS; PKG Activator; cGMP-dependent protein kinase activator; 8-(4-Chlorophenylthio)-cGMPS sodium salt; Sp-8-CPT-cGMPS; Sp-8-pCPT-cyclic GMPS sodium salt
EINECS	Contact for details

Quality Control

Our Sp-8-Pcpt-Cgmps Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.