Description

Norbiotinamine Hydrochloride CAS NO 160385-86-4 is a high-purity, advanced pharmaceutical intermediate and biochemical reagent. This compound is critical for research and development in targeted bioconjugation and molecular probe synthesis, offering a key functional handle for attaching biotin or other ligands. It is primarily utilized by pharmaceutical R&D teams, diagnostic kit manufacturers, and academic research institutions focused on life sciences and chemical biology.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those utilizing biotin-avidin technology for targeted delivery.
• Bioconjugation Reagent: Used for the site-specific labeling of proteins, antibodies, and other biomolecules to create probes for diagnostic and research applications.
• Molecular Probe Development: Essential for constructing affinity probes, imaging agents, and biosensors in chemical biology and diagnostic assay development.
• Life Science Research: Employed in academic and industrial R&D for studying protein-protein interactions, cellular uptake mechanisms, and biomarker discovery.
• Diagnostic Kit Component: Integrated into the manufacturing of ELISA kits, lateral flow assays, and other in-vitro diagnostic (IVD) products that rely on high-affinity binding systems.

Basic Information

Product Name	Norbiotinamine Hydrochloride
CAS No.	160385-86-4
Molecular Formula	C10H20N4O2S • HCl
Molecular Weight	304.82 g/mol
Synonyms	Norbiotinamine HCl; D-Biotinamine, norbiotinamine, hydrochloride; (+)-Biotinamidocaproyl-4-azidoaniline; Biotin-X, SE; 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentan-1-amine hydrochloride; Biotin Pentylamine Hydrochloride; Biotinamidocaproylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our Norbiotinamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability. Keep the container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.