Description

C-Reactive Protein (174-185) CAS NO 160369-86-8 is a synthetic peptide fragment corresponding to a specific sequence of the human C-reactive protein (CRP), a key biomarker of inflammation. This high-purity peptide is critical for advanced research and diagnostic assay development, enabling precise study of immune responses and protein interactions. It is primarily utilized by pharmaceutical R&D teams, diagnostic kit manufacturers, and academic research institutions focused on immunology, cardiovascular disease, and inflammatory disorders.

Application

• Biomarker Research & Validation: Used as a reference standard and immunogen in studies investigating the role of CRP in systemic inflammation, cardiovascular risk, and infection.
• Diagnostic Assay Development: Serves as a critical antigen for the production and calibration of antibodies in ELISA, chemiluminescence, and lateral flow immunoassays.
• Antibody Production & Epitope Mapping: Essential for generating and characterizing monoclonal and polyclonal antibodies specific to this CRP epitope.
• Pharmaceutical R&D: Employed in drug discovery programs targeting inflammatory pathways, for screening and mechanistic studies.
• Quality Control (QC) Standards: Acts as a purity and identity reference standard for in-house QC of diagnostic reagents and kits.
• Academic & Clinical Studies: Facilitates fundamental research into protein structure-function relationships and the molecular basis of inflammation.

Basic Information

Item	Details
Product Name	C-Reactive Protein (174-185)
CAS No.	160369-86-8
Molecular Formula	C58H94N18O19
Molecular Weight	1291.5 g/mol
Synonyms	CRP (174-185); Human C-Reactive Protein Fragment 174-185; CRP Peptide (174-185); H-Cys-Gln-Leu-Ala-Glu-Phe-Glu-Ala-Phe-Val-Asp-Gly-OH; C-Reactive Protein Peptide; Inflammation Biomarker Peptide; Synthetic CRP Epitope
EINECS	Contact for details

Quality Control

Every batch of C-Reactive Protein (174-185) is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with research-grade standards. Comprehensive Certificates of Analysis (COA) detailing purity, amino acid analysis, and peptide content are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Within ± 10% of theoretical
Peptide Content	≥ 70% (by weight)
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.