Description

Boc-D-Pyr-Oh CAS NO 160347-90-0 is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical chiral building block, enabling the precise construction of complex peptide structures with defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the incorporation of the D-proline analog into peptide chains.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptides and small proteins requiring specific conformational control.
• Pharmaceutical Research & Development: Serves as a building block for creating peptide-based drug candidates, including hormone analogs and enzyme inhibitors.
• Peptidomimetic Design: Integral for developing non-peptide compounds that mimic the structure and function of natural peptides.
• Bioconjugation: Can be used to attach peptide sequences to other molecules, such as dyes, polymers, or drug delivery vehicles.
• Academic Research: Employed in studies exploring protein folding, structure-activity relationships (SAR), and novel synthetic methodologies.

Basic Information

Product Name	Boc-D-Pyr-Oh
CAS No.	160347-90-0
Molecular Formula	C10H17NO4
Molecular Weight	215.25 g/mol
Synonyms	(2R)-1-[(2-Methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid; tert-Butyloxycarbonyl-D-proline; Boc-D-proline; BOC-D-PRO-OH; (R)-1-Boc-pyrrolidine-2-carboxylic acid; N-Boc-D-proline; D-Proline, N-[(1,1-dimethylethoxy)carbonyl]-; (R)-1-(tert-Butoxycarbonyl)pyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Boc-D-Pyr-Oh is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.