Description

Granisetron Nitrogen Oxide is a key pharmaceutical intermediate and research chemical. This compound is of significant interest for its role in the development and synthesis of advanced antiemetic agents. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of new drug formulations and chemical synthesis pathways. The material is handled under controlled conditions to ensure its integrity for high-value applications.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of Granisetron and its related analogs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and new drug discovery projects.
• Process Chemistry: Serves as a building block in the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing processes.
• Analytical Reference Standard: Employed as a high-purity standard for quality control and analytical method development (e.g., HPLC, LC-MS).
• Chemical Synthesis: Utilized in organic synthesis for introducing specific functional groups or creating novel molecular architectures.

Basic Information

Product Name	Granisetron Nitrogen Oxide
CAS No.	160177-68-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-Methyl-N-((1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide N-oxide; Granisetron N-Oxide; Granisetron Oxide; 1-Methyl-1H-indazole-3-carboxylic acid (1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]non-3-yl ester N-oxide
EINECS	Contact for details

Quality Control

Our Granisetron Nitrogen Oxide is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.