Description

Cyclohexanone, 4-(3,4,5-Trifluorophenyl)- CAS NO 160148-05-0 is a high-value, fluorinated organic intermediate characterized by its unique cyclohexanone core substituted with a trifluorophenyl group. This structure makes it a critical building block for synthesizing advanced molecules with enhanced properties like metabolic stability and lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated compounds used in electronic displays due to its ability to influence molecular alignment and stability.
• Advanced Polymer Chemistry: Employed in the synthesis of specialty polymers and coatings to impart specific chemical resistance and surface properties.
• Organic Electronic Materials: Acts as a building block for charge-transport or emissive materials in OLEDs and other organic electronic devices.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D exploring new fluorination chemistry and structure-activity relationships.

Basic Information

Product Name	Cyclohexanone, 4-(3,4,5-Trifluorophenyl)-
CAS No.	160148-05-0
Molecular Formula	C12H9F3O
Molecular Weight	226.19 g/mol
Synonyms	4-(3,4,5-Trifluorophenyl)cyclohexanone; 1-(3,4,5-Trifluorophenyl)-4-cyclohexanone; 3,4,5-Trifluorophenylcyclohexanone; 4-Cyclohexyl-3,4,5-trifluorobenzene-1-one; (3,4,5-Trifluorophenyl)cyclohexanone; 4-(Perfluorophenyl)cyclohexanone (common name variant); TFP-CHO (abbreviation)
EINECS	Contact for details

Quality Control

Our Cyclohexanone, 4-(3,4,5-Trifluorophenyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.