Description

Phospholipase A2 Inhibitory Protein, Naja Naja Kaouthia CAS NO 160082-09-7 is a highly specific, bioactive protein isolated from the venom of the monocled cobra (*Naja kaouthia*). This compound serves as a potent and selective inhibitor of phospholipase A2 (PLA2) enzymes, which are key mediators in inflammatory pathways and cellular signaling. It is an essential research tool for biochemists, pharmacologists, and toxicologists studying inflammation, neurobiology, and venom toxicology, with critical applications in drug discovery and the development of novel anti-inflammatory therapeutics.

Application

• Biochemical Research: Used as a specific inhibitor to study the structure, function, and catalytic mechanism of phospholipase A2 enzymes in vitro.
• Inflammation & Immunology Studies: A key reagent for investigating the role of PLA2 in inflammatory cascades, eicosanoid production, and related disease models.
• Neuroscience Research: Applied in studies exploring the neurotoxic effects of snake venom and the involvement of PLA2 in neurological disorders.
• Drug Discovery & Screening: Serves as a reference standard and tool compound in high-throughput screening assays to identify new PLA2 inhibitors.
• Toxicology & Antivenom Development: Used to understand venom toxicity mechanisms and in the research and quality control of antivenom sera.
• Academic & Pharmaceutical R&D: Essential for basic research and preclinical development within university laboratories and pharmaceutical R&D departments.

Basic Information

Product Name	Phospholipase A2 Inhibitory Protein, Naja Naja Kaouthia
CAS No.	160082-09-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PLA2 Inhibitor from *Naja kaouthia*; Cobra Venom PLA2 Inhibitor; Phospholipase A2 Inhibitory Factor; Naja naja kaouthia PLA2 Inhibitor Protein; NNKa-PLA2I; Venom-derived PLA2 Inhibitor; Anti-phospholipase A2 Protein
EINECS	Contact for details

Quality Control

Our Phospholipase A2 Inhibitory Protein is produced and handled under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot is characterized using advanced analytical techniques, including SDS-PAGE, HPLC, and functional activity assays. Certificates of Analysis (COA) detailing purity, protein concentration, and specific inhibitory activity are provided to guarantee it meets the exacting standards required for critical life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting to avoid repeated freeze-thaw cycles and store under desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Single band corresponding to expected molecular weight
Purity (HPLC)	≥ 95%
Protein Content	≥ 90% (by weight)
Biological Activity	≥ 90% inhibition of target PLA2 at specified concentration
Endotoxin Level	< 1.0 EU/mg
Solubility	Soluble in aqueous buffers or specified reconstitution solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.