Description

tert-Butyl Octahydropyrrolo[3.4-B]Pyridine-1-Carboxylate is a protected bicyclic amine derivative, serving as a crucial advanced intermediate in organic synthesis. Its value lies in providing a versatile nitrogen-containing scaffold that is essential for constructing complex molecular architectures. This compound is primarily needed by pharmaceutical and agrochemical research organizations for the development of new active ingredients, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those containing fused pyrrolidine-piperidine (octahydropyrrolopyridine) core structures.
• Medicinal Chemistry Research: Used in the exploration of structure-activity relationships (SAR) for targets such as kinases, GPCRs, and ion channels.
• Agrochemical Synthesis: Serves as a precursor for developing new crop protection agents with potential insecticidal or fungicidal activity.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.
• Academic Research: Employed in university and institutional labs for methodological development in heterocyclic and asymmetric synthesis.

Basic Information

Product Name	tert-Butyl Octahydropyrrolo[3.4-B]Pyridine-1-Carboxylate
CAS No.	159991-07-8
Molecular Formula	C12H21NO2
Molecular Weight	211.30 g/mol
Synonyms	1-Boc-Octahydropyrrolo[3,4-b]pyridine; tert-Butyl 1,3,3a,4,6,6a-hexahydro-2H-pyrrolo[3,4-b]pyridine-2-carboxylate; 1-Boc-1,3,3a,4,6,6a-hexahydro-2H-pyrrolo[3,4-b]pyridine; 2H-Pyrrolo[3,4-b]pyridine-2-carboxylic acid, 1,3,3a,4,6,6a-hexahydro-, 1,1-dimethylethyl ester; Boc-Octahydropyrrolopyridine; 1-N-Boc-Octahydropyrrolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl Octahydropyrrolo[3.4-B]Pyridine-1-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your research and development needs with reliable, high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.