Description

Adrenomedullin 1-50, Rat is a bioactive peptide fragment corresponding to the N-terminal region of the full-length adrenomedullin hormone. This specific sequence is a critical research tool for investigating cardiovascular regulation, vascular tone, and related endocrine pathways. It is essential for researchers and developers in the fields of cardiovascular pharmacology, endocrinology, and peptide-based therapeutic discovery who require high-purity, well-characterized biomolecules for reliable experimental results.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of blood pressure regulation, vascular function, and heart failure mechanisms.
• Pharmacological Assay Development: Serves as a key ligand in receptor binding studies and functional assays to screen for adrenomedullin receptor agonists or antagonists.
• Antibody Production & Immunoassay: Acts as an immunogen for generating specific antibodies or as a calibrator in ELISA and RIA kits for quantifying adrenomedullin levels.
• Signal Transduction Studies: Employed to elucidate intracellular signaling pathways (e.g., cAMP, nitric oxide) activated by adrenomedullin receptor engagement.
• Preclinical Model Studies: Administered in animal models to study its in vivo effects on hemodynamics, renal function, and inflammation.
• Peptide Chemistry & Analog Synthesis: Provides a core structure for the design and synthesis of novel peptide analogs with modified biological activity or stability.

Basic Information

Product Name	Adrenomedullin 1-50, Rat
CAS No.	159964-38-2
Molecular Formula	C245H386N72O71S2
Molecular Weight	5545.3 g/mol
Synonyms	ADM (1-50), Rat; Adrenomedullin (1-50) (rat); rADM(1-50); Preproadrenomedullin N-terminal 20 peptide (rat); Tryptophan-50-adrenomedullin (1-50), rat; AM (1-50); ADM-50
EINECS	Contact for details

Quality Control

Our Adrenomedullin 1-50, Rat is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting to minimize freeze-thaw cycles and maintain stability.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.