Description

Antithrombin Rouen-Vi is a specific variant of the serine protease inhibitor antithrombin, a critical regulator of the blood coagulation cascade. This high-purity biological compound is essential for research and development in hematology and thrombosis, providing a key tool for studying coagulation disorders and developing therapeutic interventions. It is primarily utilized by pharmaceutical R&D teams, diagnostic manufacturers, and academic research institutions focused on cardiovascular diseases and hemostasis.

Application

• Biochemical Research: Used as a standard or reagent in studies of blood coagulation pathways, enzyme kinetics, and inhibitor mechanisms.
• Diagnostic Development: Serves as a critical component in the calibration and validation of diagnostic assays for antithrombin deficiency and related thrombophilic conditions.
• Pharmaceutical R&D: Employed in the screening and development of novel anticoagulant and antithrombotic therapies.
• Reference Standard: Acts as a purified reference material for quality control in the production of therapeutic proteins and plasma-derived products.
• Cell Culture & Protein Studies: Utilized in experimental models to investigate the role of antithrombin in cellular processes and inflammation.

Basic Information

Product Name	Antithrombin Rouen-Vi
CAS No.	159940-57-5
Molecular Formula	Data on request
Molecular Weight	~58 kDa
Synonyms	Antithrombin III Rouen-Vi; ATIII Rouen-Vi; Serpin C1 variant; Antithrombin III (human plasma variant); AT III; Heparin Cofactor I; Antithrombin III Budapest; Antithrombin III Basel
EINECS	Contact for details

Quality Control

Our Antithrombin Rouen-Vi is produced and handled under strict quality protocols to ensure batch-to-batch consistency and biological activity. Each lot is characterized for purity, identity, and functional activity using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing specifications, test methods, and results is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under controlled, dry conditions to prevent degradation. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (SDS-PAGE)	≥ 95%
Assay (Functional Activity)	≥ 90% of stated activity
Protein Content	By UV absorbance
Endotoxin	< 1.0 EU/mg
Moisture (Karl Fischer)	< 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.