Description

Dmb-Caged-Atp CAS NO 159899-51-1 is a photolabile, biologically inactive derivative of adenosine triphosphate (ATP) designed for precise spatiotemporal control in cellular research. This compound matters because it allows researchers to release active ATP with high temporal precision upon exposure to UV light, enabling the study of fast ATP-dependent processes. It is an essential tool for scientists in neurobiology, cell signaling, and muscle physiology who require controlled initiation of energy-dependent reactions.

Application

• Photolysis Studies: Used as a caged compound for rapid, light-triggered release of ATP in kinetic experiments.
• Neuroscience Research: Investigating the role of ATP as a neurotransmitter or co-transmitter in synaptic transmission and neural circuits.
• Cell Signaling Pathways: Precise activation of ATP-dependent kinases, pumps, and receptors to map signaling cascades.
• Muscle Physiology: Studying the kinetics of ATP hydrolysis and energy transfer in muscle contraction models.
• Enzyme Mechanism Analysis: Time-resolved studies of ATPase and ATP-dependent enzyme activities.
• High-Throughput Screening (HTS): As a tool compound in assays requiring controlled ATP delivery.

Basic Information

Product Name	Dmb-Caged-Atp
CAS No.	159899-51-1
Molecular Formula	C₂₀H₂₅N₆O₁₃P₃
Molecular Weight	650.36 g/mol
Synonyms	P3-[1-(4,5-Dimethoxy-2-nitrophenyl)ethyl] Adenosine 5'-Triphosphate; 4,5-Dimethoxy-2-nitrobenzyl Caged ATP; DMNB-Caged ATP; DMB-caged-ATP; NPE-caged ATP analog; (2-Nitrophenyl)ethyl-caged ATP derivative; Adenosine 5'-triphosphate, P3-[1-[2-(4,5-dimethoxy-2-nitrophenyl)ethyl] ester]; "Caged" ATP, DMNB
EINECS	Contact for details

Quality Control

Our Dmb-Caged-Atp is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive life science research. Each lot undergoes comprehensive analytical testing including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your research compliance and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (UV/VIS)	≥ 90% (as caged ATP)
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, DMSO, or buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.