Description

Boc-D-Orn-Oh is a protected derivative of the non-proteinogenic amino acid D-Ornithine, featuring a tert-butoxycarbonyl (Boc) protecting group on the α-amino functionality. This compound is a critical chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic probes, and biochemical tools. The product is supplied as a high-purity material to ensure reliable and reproducible results in demanding synthetic applications.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the solid-phase and solution-phase synthesis of peptide-based drugs and bioactive compounds.
• Research Chemical: Used in academic and industrial R&D for studying enzyme-substrate interactions, metabolic pathways, and as a precursor for labeled compounds.
• Peptidomimetic Design: Integral for creating modified peptide structures with enhanced stability, bioavailability, or specific biological activity.
• Bioconjugation: Acts as a linker or spacer molecule in the preparation of antibody-drug conjugates (ADCs) and other bioconjugates.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	Boc-D-Orn-Oh
CAS No.	159877-12-0
Molecular Formula	C₁₀H₂₀N₂O₄
Molecular Weight	232.28 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-D-ornithine; (R)-2-((tert-Butoxycarbonyl)amino)-5-aminopentanoic acid; Boc-D-Ornithine; Boc-D-Orn-OH; BOC-D-ORN; D-Ornithine, N2-[(1,1-dimethylethoxy)carbonyl]-; N-(tert-Butoxycarbonyl)-D-ornithine
EINECS	Contact for details

Quality Control

Our Boc-D-Orn-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination, chiral analysis to confirm stereochemical integrity, and identity confirmation via IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	+15.0° to +18.0° (c=1 in AcOH)
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.