Description

2-(2,4-Difluorophenyl)-2-Propenyl-Propanedioic Acid Diethyl Ester is a high-purity fluorinated organic intermediate of significant commercial importance. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly for introducing the 2,4-difluorophenyl moiety. It is primarily sought after by pharmaceutical research and development teams and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and complex specialty molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, leveraging the biological activity of the difluorophenyl group.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the exploration of new fluorination and coupling reactions.

Basic Information

Product Name	2-(2,4-Difluorophenyl)-2-Propenyl-Propanedioic Acid Diethyl Ester
CAS No.	159276-62-7
Molecular Formula	C₁₆H₁₈F₂O₄
Molecular Weight	312.31 g/mol
Synonyms	Diethyl 2-(2,4-Difluorophenyl)-2-propenylpropanedioate; Diethyl (2,4-Difluorobenzyl)malonate derivative; Propanedioic acid, 2-(2,4-difluorophenyl)-2-propenyl-, diethyl ester; 2-(2,4-Difluorobenzyl)acrylic acid diethyl malonate adduct; (2,4-Difluorophenyl)allylmalonic acid diethyl ester; Allyl(2,4-difluorophenyl)malonic acid diethyl ester
EINECS	Contact for details

Quality Control

Our production of 2-(2,4-Difluorophenyl)-2-Propenyl-Propanedioic Acid Diethyl Ester adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support customer audits and regulatory submissions as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.