Description

Acetamide, n-(3,3,3-Trifluoro-2-oxopropyl)- is a specialized fluorinated acetamide derivative, identified by CAS NO 159189-10-3. This compound serves as a critical building block in advanced organic synthesis, valued for its trifluoromethyl ketone moiety which imparts unique electronic and steric properties to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in protease inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored surface properties.
• Fluorine Chemistry Research: An essential reagent for studying nucleophilic addition reactions to trifluoromethyl ketones and related transformations.
• Ligand and Catalyst Development: Used to construct complex chelating ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Acetamide, n-(3,3,3-Trifluoro-2-oxopropyl)-
CAS No.	159189-10-3
Molecular Formula	C5H6F3NO2
Molecular Weight	169.10 g/mol
Synonyms	N-(3,3,3-Trifluoro-2-oxopropyl)acetamide; 1,1,1-Trifluoro-3-(acetylamino)-2-propanone; 3-(Acetylamino)-1,1,1-trifluoro-2-propanone; 4,4,4-Trifluoro-3-oxobutanamide; Acetamide, N-(3,3,3-trifluoro-2-oxopropyl)-; 3-Acetamido-1,1,1-trifluoroacetone
EINECS	Contact for details

Quality Control

Our production of Acetamide, n-(3,3,3-Trifluoro-2-oxopropyl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.