Description

(S)-3-(Oxiran-2-Ylmethoxy)Benzonitrile is a high-purity chiral epoxide derivative, a critical building block in advanced organic synthesis. Its value lies in its ability to introduce stereochemical complexity and functional diversity into target molecules with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drug candidates, especially in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a versatile electrophile in nucleophilic ring-opening reactions to construct complex molecules with defined stereocenters.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as epoxidation or hydroxylation reactions.
• Agrochemical Research: Employed in the development of chiral active ingredients for herbicides, fungicides, and pesticides.
• Material Science: A monomer or cross-linking agent for creating specialized polymers with unique optical or mechanical properties.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(S)-3-(Oxiran-2-Ylmethoxy)Benzonitrile
CAS No.	159183-52-5
Molecular Formula	C10H9NO2
Molecular Weight	175.18 g/mol
Synonyms	(S)-3-(Oxiranylmethoxy)benzonitrile; (S)-3-(2-Oxiranylmethoxy)benzonitrile; (S)-3-Glycidyloxybenzonitrile; (S)-α,β-Epoxy-m-cyanophenetole; (2S)-2-[(3-Cyanophenoxy)methyl]oxirane; Benzonitrile, 3-[(2S)-oxiranylmethoxy]-; (S)-(-)-3-(Oxiran-2-ylmethoxy)benzonitrile
EINECS	Contact for details

Quality Control

Our (S)-3-(Oxiran-2-Ylmethoxy)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.