Description

Guanylate Cyclase Activating Protein CAS NO 159037-04-4 is a high-purity biochemical reagent that functions as a key modulator of guanylate cyclase activity. This compound is critical for researchers investigating intracellular signaling pathways, particularly those involving cyclic GMP (cGMP) as a second messenger. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on cardiovascular, neurological, and sensory biology studies.

Application

• Biochemical Research: Used as a specific activator in enzymatic assays to study guanylate cyclase function and regulation.
• Pharmaceutical Development: Serves as a reference standard and tool compound in drug discovery programs targeting cGMP-related pathways for conditions like hypertension and heart failure.
• Cell Signaling Studies: Employed to elucidate the role of cGMP in cellular processes such as phototransduction in the retina and vasodilation.
• Diagnostic Reagent Manufacturing: A potential component in the formulation of specialized diagnostic kits for research use.
• Academic & Institutional Labs: Fundamental reagent for graduate and post-doctoral research in molecular pharmacology and cell biology.

Basic Information

Product Name	Guanylate Cyclase Activating Protein
CAS No.	159037-04-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GCAP; Guanylyl Cyclase Activating Protein; GCAP-1 (related family); Retinal Guanylate Cyclase Activator; cGMP Synthesis Activator; Photoreceptor Guanylate Cyclase Regulator; Signal Transduction Protein GCAP
EINECS	Contact for details

Quality Control

Our Guanylate Cyclase Activating Protein is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including purity verification and functional activity assays, to ensure consistency and reliability for critical research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and biological activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity (Enzymatic Assay)	Conforms to standard
Water Content (KF)	≤ 5.0%
Endotoxin Level (LAL)	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.