Description

3-Fluoro-5-(Trifluoromethyl)Benzene Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Enables the creation of novel fluorinated polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical aryl boronic acid reagent for palladium-catalyzed coupling reactions to form biaryl structures.
• Chemical Research & Development: A versatile reagent for medicinal chemistry and process R&D in both academic and industrial laboratories.
• Ligand Synthesis: Precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethyl)Benzene Boronic Acid
CAS No.	159020-59-4
Molecular Formula	C7H5BF4O2
Molecular Weight	207.92 g/mol
Synonyms	[3-Fluoro-5-(trifluoromethyl)phenyl]boronic acid; 3-Fluoro-5-trifluoromethylbenzeneboronic acid; 3-Fluoro-5-(trifluoromethyl)phenylboronic acid; (3-Fluoro-5-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[3-fluoro-5-(trifluoromethyl)phenyl]-; 5-Trifluoromethyl-3-fluorobenzeneboronic acid; 3-Fluoro-alpha,alpha,α-trifluoro-m-tolueneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Trifluoromethyl)Benzene Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.