Description

Glucagon-37 (Human, Mouse, Rat) is a synthetic peptide fragment of the glucagon hormone, identified by CAS NO 159002-68-3. This high-purity research-grade compound is essential for advancing scientific understanding of metabolic regulation and receptor interaction studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology, diabetes research, and peptide-based therapeutic development.

Application

• Biomedical Research: Fundamental studies on glucagon receptor (GCGR) binding, activation, and downstream signaling pathways.
• Drug Discovery & Development: A critical reference standard and tool compound for screening and developing novel therapeutics targeting type 2 diabetes and metabolic disorders.
• In Vitro & In Vivo Assays: Used in cell-based assays and animal model studies (human, mouse, rat) to investigate glucagon's role in glucose homeostasis and liver function.
• Structure-Activity Relationship (SAR) Studies: Serves as a core structure for modifying peptide sequences to enhance potency, selectivity, and stability for potential drug candidates.
• Analytical Standard: Employed as a certified reference material in HPLC, LC-MS, and other analytical methods for method validation and quality control of related peptide products.

Basic Information

Product Name	Glucagon-37 (Human, Mouse, Rat)
CAS No.	159002-68-3
Molecular Formula	C186H285N51O59S
Molecular Weight	4179.7 g/mol
Synonyms	Glucagon (1-37), human; H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH; Glucagon 1-37; Glucagon Fragment 1-37; Glucagon-37 Peptide; GCGR Ligand (1-37); Glucagon (human) (1-37)
EINECS	Contact for details

Quality Control

Our Glucagon-37 (Human, Mouse, Rat) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and impurity profiles are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.