Description

2-Oxazolidinone, 3-(Trifluoroacetyl)- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, particularly those requiring the introduction of a trifluoroacetyl-protected oxazolidinone moiety. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for antibiotics and other bioactive molecules containing the oxazolidinone pharmacophore.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoroacetyl group can impart desirable properties like metabolic stability.
• Chiral Auxiliary & Catalyst Precursor: Serves as a precursor for developing chiral auxiliaries or organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Peptidomimetics & Protease Inhibitors: Employed in medicinal chemistry for constructing peptidomimetic scaffolds and inhibitors targeting various proteases.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialized polymers with unique surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying biological pathways and protein function.

Basic Information

Product Name	2-Oxazolidinone, 3-(Trifluoroacetyl)- (9Ci)
CAS No.	158962-11-9
Molecular Formula	C5H4F3NO3
Molecular Weight	183.09 g/mol
Synonyms	3-(Trifluoroacetyl)-2-oxazolidinone; 3-(Trifluoroacetyl)oxazolidin-2-one; N-Trifluoroacetyl-2-oxazolidinone; 2-Oxazolidinone, 3-(trifluoroacetyl)-; 1,3-Oxazolidin-2-one, 3-(trifluoroacetyl)-; Trifluoroacetic acid oxazolidin-2-one; 158962-11-9 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Oxazolidinone, 3-(Trifluoroacetyl)- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.