Description

Ferrocene, 1-[Bis(3,5-Dimethylphenyl)Phosphino]-2-[(1R)-1-[Bis(3,5-Dimethylphenyl)Phosphino]Ethyl]-, (1S)- is a sophisticated chiral ferrocenyl phosphine ligand, a critical component in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition-metal-catalyzed reactions, enabling the production of optically pure intermediates. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for synthesizing chiral molecules.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediate synthesis.
• Catalyst component for enantioselective C-C bond formation (e.g., cross-coupling, allylic substitution).
• Key reagent in the development of novel catalytic processes for academic and industrial R&D.
• Production of optically active agrochemicals and flavors/fragrances.
• Use in homogeneous catalysis research to study structure-activity relationships.
• Precursor for the synthesis of more complex chiral organometallic catalysts.

Basic Information

Item	Details
Product Name	Ferrocene, 1-[Bis(3,5-Dimethylphenyl)Phosphino]-2-[(1R)-1-[Bis(3,5-Dimethylphenyl)Phosphino]Ethyl]-, (1S)-
CAS No.	158923-10-5
Molecular Formula	C42H44FeP2
Molecular Weight	666.58 g/mol
Synonyms	(S)-1-[Bis(3,5-dimethylphenyl)phosphino]-2-[(R)-1-[bis(3,5-dimethylphenyl)phosphino]ethyl]ferrocene; Josiphos SL-J009-1; (S)-1-[(R)-2-(Bis(3,5-dimethylphenyl)phosphino)ferrocenyl]ethyldi(3,5-dimethylphenyl)phosphine; Chiral Josiphos ligand; (S)-[(R)-2-(Bis(3,5-dimethylphenyl)phosphino)ferrocenyl]ethyldi(3,5-dimethylphenyl)phosphine; (S)-1-[(R)-1-[Bis(3,5-dimethylphenyl)phosphino]ethyl]-2-(di(3,5-dimethylphenyl)phosphino)ferrocene; (S,R)-Josiphos ligand derivative
EINECS	Contact for details

Quality Control

Our production of this high-value chiral ligand adheres to strict quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot is characterized by NMR, HPLC, and chiral analysis to confirm chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific rotation is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.