Description

Aquaporin 3 is a specific isoform of the aquaporin family of integral membrane proteins that function as water and glycerol channels. This compound is of significant interest in biochemical and pharmaceutical research for its role in cellular hydration, skin physiology, and glycerol metabolism. It is primarily utilized by researchers and developers in the life sciences sector focusing on membrane biology, dermatology, and metabolic disorders. The product with CAS number 158801-98-0 is supplied as a high-purity biochemical for research and development applications.

Application

• Biochemical Research: Used as a standard or reagent in studies investigating the structure, function, and regulation of aquaglyceroporins.
• Drug Discovery: Serves as a target protein in screening assays for developing modulators of water and glycerol transport for therapeutic applications.
• Dermatological Studies: Employed in research exploring skin hydration, barrier function, and the pathophysiology of conditions like atopic dermatitis.
• Cell Biology: Utilized in cell culture and transfection experiments to study the role of AQP3 in cell proliferation, migration, and tumor biology.
• Diagnostic Development: Acts as an antigen for the production of antibodies used in immunohistochemistry, ELISA, and other detection methods.
• Metabolic Research: Applied in investigations of glycerol metabolism and its connection to energy homeostasis and insulin sensitivity.

Basic Information

Product Name	Aquaporin 3
CAS No.	158801-98-0
Molecular Formula	Information varies by preparation (Recombinant protein)
Molecular Weight	~30-35 kDa (dependent on expression system and tags)
Synonyms	AQP-3; Aquaglyceroporin-3; AQP3 Protein; Water Channel Aquaporin 3; Glycerol Facilitator; AQP3 Human; Recombinant Aquaporin 3; Major Intrinsic Protein 3
EINECS	Contact for details

Quality Control

Our Aquaporin 3 is produced and tested under stringent conditions to ensure batch-to-batch consistency and biological activity. Quality is verified through a series of analytical techniques including SDS-PAGE, Western Blot, and functional transport assays. A comprehensive Certificate of Analysis (COA) detailing purity, concentration, buffer composition, and biological activity is provided with each shipment to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use. Handle according to general laboratory safety practices.

Specification

Item	Specification
Appearance	Clear or slightly opalescent solution
Purity (SDS-PAGE)	> 90%
Identification (Western Blot)	Positive for AQP3
Protein Concentration	Provided on COA (typically 0.1-1.0 mg/mL)
Buffer	Tris, PBS, or other specified buffer
Biological Activity	Confirmed by functional assay (e.g., stopped-flow light scattering)
Endotoxin Level	< 1.0 EU/µg (for cell culture applications)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.