Description

Cyclopropanecarboxylic Acid, 1-(Aminocarbonyl)-2-Ethenyl-, cis- (9Ci) is a specialized, high-purity chemical intermediate featuring a unique cis-configured cyclopropane ring system. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise stereochemistry essential for pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, where the cyclopropane moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Incorporated into peptide analogs to confer conformational rigidity and metabolic stability for drug discovery programs.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic and R&D Laboratories: Utilized in fundamental organic chemistry research to explore new synthetic methodologies and reaction pathways.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-(Aminocarbonyl)-2-Ethenyl-, cis- (9Ci)
CAS No.	158665-23-7
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	cis-1-Carbamoyl-2-vinylcyclopropanecarboxylic Acid; (1S,2S)-1-Carbamoyl-2-vinylcyclopropanecarboxylic Acid; (1R,2R)-1-Carbamoyl-2-vinylcyclopropanecarboxylic Acid; 2-Vinyl-1-carbamoylcyclopropanecarboxylic acid, cis-; 1-Carbamoyl-2-vinylcyclopropanecarboxylic acid; NSC 339586; cis-2-Ethenyl-1-(aminocarbonyl)cyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-(Aminocarbonyl)-2-Ethenyl-, cis- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% cis-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.