Description

2-Azetidinone, 4-Ethynyl-3-Methoxy-, trans- (9Ci) is a specialized β-lactam derivative, a key structural motif in medicinal chemistry. This compound matters as a versatile and high-value chemical building block for the synthesis of novel pharmaceutical intermediates and active ingredients. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries, where its unique trans-configured azetidinone ring and ethynyl moiety enable the construction of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel β-lactam antibiotics and other therapeutic agents targeting bacterial infections.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Organic Synthesis Building Block: Utilized in advanced organic transformations, including click chemistry via its ethynyl group and ring-opening polymerizations.
• Agrochemical Development: Employed in the research and synthesis of new crop protection agents with novel modes of action.
• Bioconjugation Chemistry: The ethynyl functionality allows for efficient labeling and conjugation with biomolecules for diagnostic or therapeutic purposes.
• Academic & Institutional Research: Used in universities and research institutes for studying β-lactam chemistry and developing new synthetic methodologies.

Basic Information

Product Name	2-Azetidinone, 4-Ethynyl-3-Methoxy-, trans- (9Ci)
CAS No.	158612-61-4
Molecular Formula	C6H7NO2
Molecular Weight	125.13 g/mol
Synonyms	trans-4-Ethynyl-3-methoxyazetidin-2-one; 4-Ethynyl-3-methoxy-2-azetidinone, trans-; (3R,4S)-4-Ethynyl-3-methoxyazetidin-2-one; (3S,4R)-4-Ethynyl-3-methoxyazetidin-2-one; 3-Methoxy-4-ethynylazetidin-2-one; Azetidin-2-one, 4-ethynyl-3-methoxy-, trans-; 158612-61-4; A β-lactam synthon
EINECS	Contact for details

Quality Control

Our 2-Azetidinone, 4-Ethynyl-3-Methoxy-, trans- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.