Description

Propanamide, n-(4,5-Dihydro-5-thioxo-1,3,4-oxadiazol-2-yl)- is a specialized heterocyclic amide compound that serves as a key synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a fused oxadiazole-thione moiety, makes it a valuable building block for constructing complex molecules with targeted biological or material properties. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical sectors, where precise molecular architecture is critical for activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the oxadiazole scaffold is pharmacologically active.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Research & Development: Serves as a versatile building block in academic and industrial R&D for creating libraries of novel heterocyclic compounds.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or ligands for metal-organic frameworks (MOFs) due to its amide and heterocyclic functional groups.
• Bioconjugation Chemistry: The reactive amide and thione groups can be utilized for linking molecules in probe or conjugate development.

Basic Information

Product Name	Propanamide, n-(4,5-Dihydro-5-thioxo-1,3,4-oxadiazol-2-yl)-
CAS No.	158602-95-0
Molecular Formula	C5H7N3O2S
Molecular Weight	173.19 g/mol
Synonyms	2-(Propanoylamino)-1,3,4-oxadiazole-5-thiol; 2-Propanamido-5-mercapto-1,3,4-oxadiazole; N-(5-Mercapto-1,3,4-oxadiazol-2-yl)propanamide; 5-Mercapto-2-propionamido-1,3,4-oxadiazole; Propanamide, N-(5-mercapto-1,3,4-oxadiazol-2-yl)-; 1,3,4-Oxadiazole-5-thiol, 2-(propanoylamino)-; Propanimidic acid, N-(4,5-dihydro-5-thioxo-1,3,4-oxadiazol-2-yl)-
EINECS	Contact for details

Quality Control

Our Propanamide, n-(4,5-Dihydro-5-thioxo-1,3,4-oxadiazol-2-yl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for use as a pharmaceutical intermediate in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.