Description

2-Iodobenzoylacetonitrile is a versatile iodinated aromatic building block and key synthetic intermediate. This compound matters for its utility in constructing complex molecular architectures, particularly in the development of pharmaceuticals and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as heterocyclic synthesis and catalyst ligand preparation.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those containing iodinated aromatic or heterocyclic structures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for organic electronic materials, liquid crystals, and advanced polymers.
• Catalyst & Ligand Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Research: A valuable reagent for method development in organic synthesis, including cross-coupling reactions and cyclization studies.
• Dye & Pigment Industry: Acts as an intermediate in the synthesis of complex colorants and functional dyes.

Basic Information

Item	Detail
Product Name	2-Iodobenzoylacetonitrile
CAS No.	158387-19-0
Molecular Formula	C9H6INO
Molecular Weight	271.06 g/mol
Synonyms	2-Iodobenzoylacetonitrile; (2-Iodobenzoyl)acetonitrile; 3-Oxo-3-(2-iodophenyl)propanenitrile; 2-Iodobenzoyl Methyl Cyanide; α-Cyano-2-iodoacetophenone; 2-Iodophenacyl Cyanide; 1-(2-Iodophenyl)-2-cyanoethanone; Acetonitrile, (2-iodobenzoyl)-
EINECS	Contact for details

Quality Control

Our 2-Iodobenzoylacetonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.