Description

(4S)-4-Butyl-2-Oxazolidinone is a high-value chiral auxiliary and synthetic intermediate of significant importance in asymmetric organic synthesis. Its core value lies in enabling the stereoselective construction of complex molecules, which is critical for producing enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity building blocks for their synthetic workflows.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Widely used to induce stereoselectivity in aldol, alkylation, and Diels-Alder reactions.
• Pharmaceutical Intermediate: A key building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Employed in the development of chiral herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
• Catalyst and Ligand Precursor: Serves as a starting material for the preparation of specialized catalysts and ligands used in homogeneous catalysis.
• Academic and Industrial R&D: A fundamental reagent for methodological development in organic chemistry laboratories and process chemistry departments.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances where specific stereochemistry is required.

Basic Information

Product Name	(4S)-4-Butyl-2-Oxazolidinone
CAS No.	158249-51-5
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(S)-4-Butyl-2-oxazolidinone; (S)-(-)-4-Butyl-2-oxazolidinone; (4S)-(-)-4-Butyl-2-oxazolidinone; (S)-4-n-Butyl-2-oxazolidinone; L-4-Butyl-2-oxazolidinone; (S)-4-Butyloxazolidin-2-one; Evans Auxiliary Derivative; Contact for details on EINECS.

Quality Control

Our (4S)-4-Butyl-2-Oxazolidinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and standard impurity profiling via HPLC, GC, and NMR. Certificates of Analysis (COA) are available for every batch and provided upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.