Description

1,2-Difluoro-4-(Trifluoromethoxyl)Benzene is a high-purity fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both fluorine atoms and a trifluoromethoxy group, makes it a valuable precursor for creating complex molecules with tailored electronic and physical properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core component in the development of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved performance and durability.
• Polymer & Specialty Chemicals: Employed as a monomer or modifier to create high-performance polymers with enhanced chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis & Catalysis: Acts as a versatile reagent in cross-coupling reactions and as a ligand precursor in catalysis research within fine chemical manufacturing.

Basic Information

Product Name	1,2-Difluoro-4-(Trifluoromethoxyl)Benzene
CAS No.	158178-35-9
Molecular Formula	C7H3F5O
Molecular Weight	198.09 g/mol
Synonyms	1,2-Difluoro-4-(trifluoromethoxy)benzene; 3,4-Difluorophenyl trifluoromethyl ether; 4-(Trifluoromethoxy)-1,2-difluorobenzene; 1,2-Difluoro-4-(trifluoromethoxy)benzene; Benzene, 1,2-difluoro-4-(trifluoromethoxy)-; 3,4-Difluoro(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 1,2-Difluoro-4-(Trifluoromethoxyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed at room temperature (15-25°C). Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.