Description

Nibentan CAS NO 157832-56-9 is a selective class III antiarrhythmic agent, functioning as a potassium channel blocker. This compound is of significant interest in pharmaceutical research and development for its potential in treating cardiac arrhythmias. It is primarily utilized by research institutions and pharmaceutical companies engaged in cardiovascular drug discovery and development.

Application

• Cardiovascular Research: Primary application in the study and development of novel antiarrhythmic drugs targeting potassium channels.
• Pharmacological Studies: Used as a reference standard or active pharmaceutical ingredient (API) in preclinical and clinical research.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) to identify and characterize ion channel modulators.
• Mechanism of Action (MOA) Studies: Critical for investigating the electrophysiology of the heart and the role of specific potassium currents.
• Pharmaceutical Intermediates: Serves as a key synthetic intermediate in the production of more complex therapeutic agents.
• Academic Research: Utilized in university and institutional labs for fundamental studies in cardiac physiology and pharmacology.

Basic Information

Product Name	Nibentan
CAS No.	157832-56-9
Molecular Formula	C24H30N2O3S
Molecular Weight	426.58 g/mol
Synonyms	Nibentan; N-[2-(Diethylamino)ethyl]-4-[(methylsulfonyl)amino]benzamide; 4-[(Methylsulfonyl)amino]-N-[2-(diethylamino)ethyl]benzamide; LU-111995; Antiarrhythmic Agent LU-111995
EINECS	Contact for details

Quality Control

Our Nibentan is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets high-purity standards suitable for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.