Description

2-o-(o-Nitrophenyl)-α-D-n-Acetylneuraminic Acid is a specialized, high-purity chemical derivative of N-acetylneuraminic acid, a key sialic acid. This compound is engineered for advanced research and development, particularly in the fields of glycobiology and medicinal chemistry. It serves as a critical building block and analytical standard for scientists and manufacturers developing novel diagnostics, enzyme inhibitors, and carbohydrate-based therapeutics.

Application

• Glycobiology Research: A key intermediate in the synthesis of complex sialylated glycoconjugates for studying cell-cell recognition and signaling pathways.
• Enzyme Substrate/Analogue: Used in the study and inhibition of sialidases (neuraminidases) and sialyltransferases, relevant to virology and cancer research.
• Pharmaceutical Intermediate: Serves as a sophisticated precursor in the development of new antiviral agents, especially targeting influenza and other viruses that utilize sialic acid receptors.
• Diagnostic Reagent Development: Employed in the creation of sensitive assays and probes for detecting specific carbohydrate-protein interactions.
• Bioconjugation Chemistry: The nitrophenyl group provides a handle for further chemical modification and conjugation to proteins, lipids, or surfaces.
• Analytical Standard: Used as a high-purity reference standard in HPLC, LC-MS, and NMR for the quantification and identification of sialic acid derivatives.

Basic Information

Product Name	2-o-(o-Nitrophenyl)-α-D-n-Acetylneuraminic Acid
CAS No.	157707-92-1
Molecular Formula	C17H22N2O11
Molecular Weight	430.37 g/mol
Synonyms	2-(2-Nitrophenoxy)-α-D-N-acetylneuraminic acid; o-Nitrophenyl α-D-N-acetylneuraminoside; 2-O-(2-Nitrophenyl)-α-D-N-acetylneuraminic acid; N-Acetyl-2-O-(2-nitrophenyl)-α-neuraminic acid; Sialic acid o-nitrophenyl glycoside; Neu5Acα2-O-oNO2Ph; Glycoconjugate building block
EINECS	Contact for details

Quality Control

Every batch of 2-o-(o-Nitrophenyl)-α-D-n-Acetylneuraminic Acid is produced and tested under stringent quality management systems. We provide comprehensive analytical documentation to ensure traceability and reliability for your critical research and development work. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.