Description

(4-Fluoro-3-Nitrophenyl)Acetonitrile is a versatile aromatic nitrile building block characterized by its fluorinated nitrobenzene core. This compound is of significant value in advanced organic synthesis, where its reactive nitrile and electron-deficient aromatic ring enable the construction of complex heterocyclic and pharmaceutical intermediates. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials due to its electron-withdrawing properties.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing complex, color-fast dyes and pigments.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	(4-Fluoro-3-Nitrophenyl)Acetonitrile
CAS No.	157662-77-6
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	2-(4-Fluoro-3-nitrophenyl)acetonitrile; (4-Fluoro-3-nitrobenzyl) cyanide; 4-Fluoro-3-nitrobenzyl cyanide; 4-Fluoro-3-nitrophenylacetonitrile; 2-(4-Fluoro-3-nitrophenyl)ethanenitrile; α-Cyano-4-fluoro-3-nitrotoluene; 4-Fluoro-3-nitrobenzeneacetonitrile; 157662-77-6
EINECS	Contact for details

Quality Control

Every batch of (4-Fluoro-3-Nitrophenyl)Acetonitrile is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards, and our quality control includes advanced analytical techniques to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.