Description

(R)-1-Benzyl-3-Pyrrolidinecarbonitrile is a chiral pyrrolidine derivative of significant importance in asymmetric synthesis and pharmaceutical research. This compound serves as a versatile and valuable building block for the construction of complex molecules, particularly those with biological activity. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for neurological and cardiovascular targets.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of chiral ligands for metal-catalyzed asymmetric reactions, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for novel chiral pesticides and herbicides, where specific stereochemistry can influence biological activity and environmental profile.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value specialty chemicals for advanced material science and electronics applications.
• Academic & Institutional Research: Used in universities and research institutes for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(R)-1-Benzyl-3-Pyrrolidinecarbonitrile
CAS No.	157528-56-8
Molecular Formula	C12H14N2
Molecular Weight	186.25 g/mol
Synonyms	(R)-1-Benzylpyrrolidine-3-carbonitrile; (3R)-1-Benzyl-3-pyrrolidinecarbonitrile; (R)-1-Benzyl-3-cyanopyrrolidine; (R)-α-(Cyanomethyl)-N-benzylpyrrolidinemethane; 1-Benzyl-3-cyano-(R)-pyrrolidine; (R)-N-Benzyl-3-pyrrolidinecarbonitrile
EINECS	Contact for details

Quality Control

Our (R)-1-Benzyl-3-Pyrrolidinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistent quality, enantiomeric excess, and batch-to-batch reproducibility.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.