Description

2-Propenoic Acid, 3-[2-(Trifluoromethyl)Phenyl]-, Methyl Ester, (2E)- is a specialized fluorinated acrylate derivative, a high-value building block prized for its unique trifluoromethylphenyl moiety. This compound is engineered to impart enhanced chemical stability, lipophilicity, and specific electronic properties to advanced materials and pharmaceuticals. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for synthesizing novel active ingredients and functional monomers.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Specialty Polymer Monomer: Serves as a functional monomer for creating fluorinated acrylic polymers with specific properties like oil/water repellency, chemical resistance, and low surface energy.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic display and lighting technologies due to its influence on molecular polarity and alignment.
• Advanced Material Research: Utilized in academic and industrial R&D for developing new coatings, adhesives, and composites with tailored performance characteristics.
• Chemical Synthesis Building Block: Acts as a versatile reagent for introducing the 2-(trifluoromethyl)phenylacrylic acid ester group into more complex molecular architectures via cross-coupling or conjugate addition reactions.

Basic Information

Product Name	2-Propenoic Acid, 3-[2-(Trifluoromethyl)Phenyl]-, Methyl Ester, (2E)-
CAS No.	157518-53-1
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	(2E)-3-[2-(Trifluoromethyl)phenyl]-2-propenoic acid methyl ester; Methyl (2E)-3-[2-(trifluoromethyl)phenyl]acrylate; Methyl (E)-3-(2-(trifluoromethyl)phenyl)acrylate; (E)-Methyl 3-(2-(trifluoromethyl)phenyl)acrylate; 2-Propenoic acid, 3-[2-(trifluoromethyl)phenyl]-, methyl ester, (E)-; Trifluoromethylphenyl acrylic acid methyl ester; 2-(Trifluoromethyl)cinnamic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 2-Propenoic Acid, 3-[2-(Trifluoromethyl)Phenyl]-, Methyl Ester, (2E)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting critical parameters such as assay, isomeric purity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for reliable use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (E-Isomer, HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.