Description

(R)-Monophos is a high-value chiral phosphine ligand widely used in asymmetric synthesis. Its primary value lies in its ability to induce high enantioselectivity in catalytic reactions, which is critical for producing single-isomer active pharmaceutical ingredients (APIs). This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• As a chiral ligand in asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• Catalyst component for the synthesis of enantiomerically pure pharmaceutical intermediates.
• Key reagent in the development of novel agrochemicals with specific biological activity.
• Used in academic and industrial research for method development in asymmetric catalysis.
• Employed in the synthesis of complex natural products and specialty chemicals.
• Facilitates the production of chiral compounds for material science applications.

Basic Information

Item	Detail
Product Name	(R)-Monophos
CAS No.	157488-65-8
Molecular Formula	C31H32P2
Molecular Weight	466.53 g/mol
Synonyms	(R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl; (R)-BINAP; (R)-(+)-BINAP; (R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl; (R)-1,1'-Binaphthalene-2,2'-diylbis(diphenylphosphine); (R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl; (R)-(+)-1,1'-Binaphthyl-2,2'-diylbis(diphenylphosphine); BINAP, (R)-(+)
EINECS	Contact for details

Quality Control

Our (R)-Monophos is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee it meets the stringent requirements for catalytic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry place. Due to its sensitivity to oxidation, the container should only be opened in an inert environment.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.