Description

R(+)-Arachidonyl-1'-Hydroxy-2'-Propylamide is a high-purity synthetic cannabinoid receptor ligand, specifically a chiral derivative of arachidonyl ethanolamide. This compound is a critical research-grade biochemical for investigating the endocannabinoid system and its complex signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and analytical laboratories focused on neuroscience, pharmacology, and metabolic studies.

Application

• Pharmacological Research: Acts as a selective ligand for studying cannabinoid receptor (CB1/CB2) binding affinity, activation, and downstream effects in vitro and in vivo.
• Neuroscience Studies: Used to probe the role of endocannabinoid signaling in pain modulation, neuroinflammation, appetite regulation, and memory formation.
• Drug Discovery & Development: Serves as a reference standard and a key intermediate in the synthesis and screening of novel therapeutic agents targeting the endocannabinoid system.
• Biochemical Assay Development: Employed as a calibrant or control in developing high-throughput screening (HTS) assays and analytical methods (e.g., LC-MS, HPLC) for endocannabinoid analysis.
• Metabolic Pathway Analysis: A tool for investigating the biosynthesis, transport, and degradation pathways of endocannabinoid-like molecules.

Basic Information

Product Name	R(+)-Arachidonyl-1'-Hydroxy-2'-Propylamide
CAS No.	157182-49-5
Molecular Formula	C₂₃H₃₉NO₂
Molecular Weight	361.57 g/mol
Synonyms	R(+)-Arachidonyl-1'-hydroxy-2'-propylamide; (R)-Arachidonoyl-1'-hydroxy-2'-propylamide; O-2050; (5Z,8Z,11Z,14Z)-N-[(2R)-1-Hydroxypropan-2-yl]icosa-5,8,11,14-tetraenamide; R(+)-O-2050; Arachidonoyl ethanolamide derivative; R(+)-AEA analogue
EINECS	Contact for details

Quality Control

Every batch of R(+)-Arachidonyl-1'-Hydroxy-2'-Propylamide is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency for research applications. Our products undergo rigorous analytical testing, including chiral HPLC, to confirm enantiomeric purity and chemical integrity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% (R-isomer)
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.