Description

n-Desmethyl Dapoxetine CAS NO 157166-71-7 is a key pharmaceutical intermediate and a major metabolite of Dapoxetine hydrochloride. This compound is of significant value in the research and development of active pharmaceutical ingredients (APIs) and for analytical reference standards. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and quality control of therapeutics for central nervous system disorders.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of Dapoxetine hydrochloride and related compounds.
• Metabolite Reference Standard: Used in bioanalytical studies, pharmacokinetic research, and drug metabolism investigations.
• Active Pharmaceutical Ingredient (API) Research: Serves as a precursor in the development and scale-up of new therapeutic agents.
• Quality Control & Assurance: Employed as a high-purity standard for HPLC, LC-MS, and other analytical methods to ensure product purity and consistency.
• Pharmacological Studies: Used in preclinical and clinical research to understand the efficacy and safety profile of serotonergic agents.

Basic Information

Product Name	n-Desmethyl Dapoxetine
CAS No.	157166-71-7
Molecular Formula	C20H23NO
Molecular Weight	293.41 g/mol
Synonyms	(S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine; Desmethyl Dapoxetine; Dapoxetine Impurity; Dapoxetine Metabolite; (S)-1-Phenyl-3-[(1-naphthyl)oxy]propyl dimethylamine; LY-300502; LY 300502
EINECS	Contact for details

Quality Control

Our n-Desmethyl Dapoxetine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.