Description

n-((tert-Butoxycarbonyl)Alanyl-Prolyl-Phenylalanyl)-o-Benzoylhydroxylamine is a specialized synthetic peptide derivative designed for advanced research and development. This compound is a crucial building block in medicinal chemistry, serving as a key intermediate for the synthesis of protease inhibitors and other biologically active molecules. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on drug discovery and peptide-based therapeutic development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel protease inhibitors targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Bioconjugation: Serves as a specialized linker or reagent in the development of peptide-drug conjugates (PDCs) and other bioconjugates.
• Enzyme Substrate Analog: Employed in biochemical assays to study enzyme kinetics and inhibition mechanisms of specific proteases.
• Peptide Library Synthesis: A valuable component for constructing focused libraries in combinatorial chemistry for high-throughput screening.
• Academic & Institutional R&D: Supports fundamental research in biochemistry, molecular biology, and pharmacology.

Basic Information

Product Name	n-((tert-Butoxycarbonyl)Alanyl-Prolyl-Phenylalanyl)-o-Benzoylhydroxylamine
CAS No.	157135-53-0
Molecular Formula	C30H38N4O7
Molecular Weight	566.65 g/mol
Synonyms	Boc-Ala-Pro-Phe-NH-OBz; Boc-Ala-Pro-Phe-NHO-Bz; N-[(tert-Butoxycarbonyl)alanyl-prolyl-phenylalanyl]-O-benzoylhydroxylamine; (tert-Butoxycarbonyl)alanyl-prolyl-phenylalanyl benzohydroxamate; Ala-Pro-Phe-NH-OBz, Boc-; Protease Inhibitor Intermediate 157135-53-0; Peptide Hydroxamate Derivative
EINECS	Contact for details

Quality Control

Our n-((tert-Butoxycarbonyl)Alanyl-Prolyl-Phenylalanyl)-o-Benzoylhydroxylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.