Description

Cyclopentaneacetonitrile, 2,2,3-Trimethyl-, (1S-Cis)- (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant value in advanced organic synthesis. Its unique sterically hindered cyclopentane backbone and nitrile functionality make it a critical building block for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas requiring stereochemical control.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of specialty chemicals, flavors, and fragrances requiring high isomeric purity.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry and process development in pilot-scale operations.

Basic Information

Product Name	Cyclopentaneacetonitrile, 2,2,3-Trimethyl-, (1S-Cis)- (9Ci)
CAS No.	156963-30-3
Molecular Formula	C10H17N
Molecular Weight	151.25 g/mol
Synonyms	(1S,2R)-2,2,3-Trimethylcyclopentaneacetonitrile; (1S-cis)-2,2,3-Trimethylcyclopentaneacetonitrile; 2,2,3-Trimethylcyclopentaneacetonitrile, (1S-cis)-; cis-(1S)-2,2,3-Trimethylcyclopentylacetonitrile; (1S,2R)-2,2,3-Trimethyl-1-cyclopentaneacetonitrile
EINECS	Contact for details

Quality Control

Our production of Cyclopentaneacetonitrile, 2,2,3-Trimethyl-, (1S-Cis)- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chiral purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess, and impurity profile. We are committed to meeting the exacting requirements of GMP and ISO-guided environments for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.