Description

4-Fluorophenylboronic Acid-1,3-Propanediol Ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic chemistry. This compound is valued for its enhanced stability compared to its parent boronic acid, facilitating handling and storage while retaining its reactivity in key transformations. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules via cross-coupling reactions.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for introducing the 4-fluorophenyl moiety into biaryl structures, a common pharmacophore in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and synthesis of potential drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the creation of novel organic electronic materials, ligands, and functionalized polymers.
• Chemical Biology & Proteomics: Can be utilized as a tool compound or linker in bioconjugation and probe development.

Basic Information

Product Name	4-Fluorophenylboronic Acid-1,3-Propanediol Ester
CAS No.	156942-21-1
Molecular Formula	C9H10BFO3
Molecular Weight	196.99 g/mol
Synonyms	4-Fluorophenylboronic acid 1,3-propanediol cyclic ester; 2-(4-Fluorophenyl)-5-hydroxy-1,3,2-dioxaborinane; 4-Fluorobenzeneboronic acid 1,3-propanediol ester; 4-Fluorophenyl-1,3,2-dioxaborinane; 1,3-Propanediol cyclic ester with (4-fluorophenyl)boronic acid; (4-Fluorophenyl)-1,3,2-dioxaborinane; 4-Fluoro phenylboronic acid pinacol ester analog (propanediol).
EINECS	Contact for details

Quality Control

Our 4-Fluorophenylboronic Acid-1,3-Propanediol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.