Description

H-D-Lys(Z)-Obzl Hcl CAS NO 156917-23-6 is a protected amino acid derivative, specifically the hydrochloride salt of Nα-benzyloxycarbonyl-Nε-benzyloxycarbonyl-D-lysine. This compound is a critical chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutic peptides, diagnostic agents, and novel bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key D-configured lysine derivative for introducing specific side-chain protection and chirality into peptide chains.
• Pharmaceutical Intermediates: Serves as a crucial intermediate in the research and production of peptide-based drugs, including hormone analogs and enzyme inhibitors.
• Bioconjugation Chemistry: Used in the preparation of labeled peptides or peptide-carrier conjugates for diagnostic and immunological studies.
• Chemical Biology Research: Employed in the synthesis of custom peptides for studying protein-protein interactions, receptor binding, and signal transduction pathways.
• Process Development: Acts as a standard or reference material for developing and scaling up peptide manufacturing processes under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	H-D-Lys(Z)-Obzl Hcl
CAS No.	156917-23-6
Molecular Formula	C22H26N2O6 • HCl
Molecular Weight	450.91 g/mol (Free base: 414.45)
Synonyms	Nα-Cbz-Nε-Cbz-D-lysine Hydrochloride; D-Lysine, N2,N6-bis[(benzyloxy)carbonyl]-, hydrochloride (1:1); Nα-Z-Nε-Z-D-Lysine HCl; (R)-2,6-Bis((benzyloxy)carbonylamino)hexanoic acid hydrochloride; Nα-Carbobenzoxy-Nε-carbobenzoxy-D-lysine hydrochloride; H-D-Lys(Z)-Obzl•HCl; Boc-D-Lys(Z)-OH (Note: This is a common related compound, often searched in error); D-Lys(Z,Z)-OH•HCl
EINECS	Contact for details

Quality Control

Our H-D-Lys(Z)-Obzl Hcl is produced and tested under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We support compliance with relevant standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.