Description

2-Fluorocyclopropanecarboxylic Acid is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its unique strained cyclopropane ring, combined with a fluorine substituent and a carboxylic acid handle, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for chiral ligands and organocatalysts, exploiting the stereochemistry of the cyclopropane ring.
• Material Science Precursor: Employed in the synthesis of fluorinated polymers and advanced materials with specific surface properties.
• Chemical Biology Probes: Useful for incorporating fluorinated cyclopropane motifs into probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	2-Fluorocyclopropanecarboxylic Acid
CAS No.	156816-78-3
Molecular Formula	C4H5FO2
Molecular Weight	104.08 g/mol
Synonyms	2-Fluorocyclopropane-1-carboxylic acid; 1-Fluorocyclopropane-2-carboxylic acid; Cyclopropanecarboxylic acid, 2-fluoro-; 2-Fluoro-1-cyclopropanecarboxylic acid; (1R,2S)-rel-2-Fluorocyclopropanecarboxylic acid (for stereoisomer); 2-Fluorocyclopropanecarboxylate; Fluorocyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Fluorocyclopropanecarboxylic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.