Description

4-Benzyloxy-2,6-Difluorophenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex, fluorinated aromatic compounds and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing difluorophenyl and benzyloxy motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific fluorinated aromatic structures.
• Material Science: Serves as a monomer or building block for creating advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex molecular architectures via palladium-catalyzed cross-coupling.
• Ligand Synthesis: Can be utilized to prepare specialized boronic acid-based ligands for catalysis and sensor development.

Basic Information

Product Name	4-Benzyloxy-2,6-Difluorophenylboronic Acid
CAS No.	156635-89-1
Molecular Formula	C₁₃H₁₁BF₂O₃
Molecular Weight	264.04 g/mol
Synonyms	2,6-Difluoro-4-(phenylmethoxy)benzeneboronic Acid; (4-(Benzyloxy)-2,6-difluorophenyl)boronic Acid; 4-(Benzyloxy)-2,6-difluorobenzeneboronic Acid; B-[4-(Benzyloxy)-2,6-difluorophenyl]boronic Acid
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-2,6-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.