Description

3,5-Difluorophenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is critically needed by pharmaceutical R&D teams, agrochemical manufacturers, and advanced materials scientists for the development of new active ingredients and functional molecules. Its specific substitution pattern offers precise control over molecular architecture in target compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with fluorinated aromatic cores, particularly in oncology and CNS drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the difluorophenyl moiety enhances biological activity and metabolic stability.
• Material Science: Employed in the creation of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology & Diagnostics: Utilized in probe and sensor development for fluorescence labeling and bio-conjugation strategies.
• Polymer Chemistry: Incorporated as a monomer or cross-linker for specialty polymers with tailored thermal and optical properties.

Basic Information

Product Name	3,5-Difluorophenylboronic Acid
CAS No.	156545-07-2
Molecular Formula	C6H5BF2O2
Molecular Weight	157.92 g/mol
Synonyms	(3,5-Difluorophenyl)boronic acid; B-(3,5-Difluorophenyl)boronic acid; 3,5-Difluorobenzeneboronic acid; (3,5-Difluorophenyl)boronic Acid; 3,5-Difluorophenyl-Boric Acid; 3,5-Difluorophenylboronic acid (contains varying amounts of Anhydride); Boronic acid, B-(3,5-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our 3,5-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications in cGMP pharmaceutical development and other regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.