Description

4-Butoxy-3-Fluorophenylboronic Acid is a specialized organoboron compound featuring both a fluorinated aromatic ring and a butoxy substituent. This unique structure makes it a highly valuable building block in modern synthetic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise functionalization of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs), especially those containing fluorinated biaryl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorophenyl group can improve activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating advanced organic electronic materials, where the butoxy chain can influence mesomorphic and charge-transport properties.
• Polymer Chemistry: Employed in the synthesis of functionalized polymers and dendrimers with tailored properties for specialty coatings and engineering plastics.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new chemical spaces and synthesizing complex organic molecules.
• Ligand & Catalyst Design: The boronic acid group can be utilized to create novel ligands for catalysis or as a handle for further functionalization in sensor development.

Basic Information

Product Name	4-Butoxy-3-Fluorophenylboronic Acid
CAS No.	156487-13-7
Molecular Formula	C₁₀H₁₄BFO₃
Molecular Weight	212.03 g/mol
Synonyms	(4-Butoxy-3-fluorophenyl)boronic acid; 3-Fluoro-4-butoxybenzeneboronic acid; 4-Butoxy-3-fluorobenzeneboronic acid; Boronic acid, B-(4-butoxy-3-fluorophenyl)-; 156487-13-7; 4-n-Butoxy-3-fluorophenylboronic acid; 3-Fluoro-4-n-butoxyphenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-Butoxy-3-Fluorophenylboronic Acid is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using an inert atmosphere or desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.