Description

4-Butoxy-2,3-Difluorophenylboronic Acid is a specialized organoboron compound featuring a butoxy-substituted difluorophenyl ring. This chemical matters as a versatile building block in modern synthetic chemistry, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring the difluorophenyl pharmacophore.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the boronic acid moiety facilitates the introduction of complex aromatic systems.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Employed to introduce functional aromatic groups into polymer backbones, enhancing material properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form biaryl and other complex aromatic structures.

Basic Information

Item	Detail
Product Name	4-Butoxy-2,3-Difluorophenylboronic Acid
CAS No.	156487-12-6
Molecular Formula	C₁₀H₁₃BF₂O₃
Molecular Weight	230.02 g/mol
Synonyms	2,3-Difluoro-4-butoxyphenylboronic Acid; (4-Butoxy-2,3-difluorophenyl)boronic Acid; 4-n-Butoxy-2,3-difluorobenzeneboronic Acid; 156487-12-6; B-(4-Butoxy-2,3-difluorophenyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 4-Butoxy-2,3-Difluorophenylboronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.