Description

Opa Protein, Neisseria Meningitidis is a key outer membrane protein derived from the bacterium *Neisseria meningitidis*, a primary causative agent of meningococcal disease. This protein is of significant value in the research and development of diagnostic assays and vaccine candidates, as it plays a crucial role in bacterial adhesion and immune evasion. It is essential for biotechnology and pharmaceutical companies focused on infectious disease research, immunology studies, and the development of novel therapeutic and preventative biologics.

Application

• Vaccine Research & Development: Critical antigen for the study and formulation of subunit or conjugate vaccines against meningococcal serogroups.
• Diagnostic Assay Development: Used as a coating antigen or standard in ELISA, Western Blot, and other immunoassays to detect specific antibodies.
• Immunological Studies: Serves as a model antigen to investigate host-pathogen interactions, immune response mechanisms, and bacterial pathogenesis.
• Biomarker Discovery: Employed in proteomics and biomarker research to understand disease progression and identify therapeutic targets.
• Quality Control Reference: Acts as a reference standard for the quality control and potency testing of commercial vaccines and diagnostic kits.
• Antibody Production: Used to immunize animals for the generation of polyclonal or monoclonal antibodies specific to *Neisseria meningitidis*.

Basic Information

Item	Detail
Product Name	Opa Protein, Neisseria Meningitidis
CAS No.	156319-92-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Outer Membrane Protein Opacity Protein; Meningococcal Opa Protein; Neisserial Opacity Protein; OMP Opacity Protein; Protein Opa; Opacity-associated Adhesin; Phase-variable Opa; *Neisseria meningitidis* Outer Membrane Protein
EINECS	Contact for details

Quality Control

Our Opa Protein is produced and purified under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation, and endotoxin level determination. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein aliquots should be stored at -70°C to -80°C and avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or desiccant when not in use.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE/Western Blot)	Conforms
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA/Bradford)	≥ 95% of total mass
Endotoxin (LAL)	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers
Biological Activity (ELISA/Binding)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.