Description

2-Amino-2-Methyl-Butyric Acid Methyl Ester Hydrochloride is a high-purity, protected amino acid derivative essential for advanced organic synthesis. Its primary value lies in serving as a key chiral building block for the development of pharmaceuticals and bioactive compounds, enabling precise molecular construction. This intermediate is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of peptidomimetics and enzyme inhibitors.
• Agrochemical Research: Used as a building block in the design and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Employed in solid-phase and solution-phase peptide synthesis to introduce sterically hindered, non-proteinogenic amino acid residues.
• Fine Chemical Synthesis: Serves as a versatile intermediate for creating specialty chemicals, flavors, fragrances, and advanced materials.
• Bioconjugation & Linker Chemistry: Useful in the preparation of chemical linkers and for bioconjugation applications in drug delivery systems.
• Academic & Industrial R&D: A valuable reagent for methodological development in asymmetric synthesis and for exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	2-Amino-2-Methyl-Butyric Acid Methyl Ester Hydrochloride
CAS No.	156032-14-3
Molecular Formula	C7H16ClNO2
Molecular Weight	181.66 g/mol
Synonyms	Methyl 2-Amino-2-methylbutanoate hydrochloride; 2-Methyl-2-aminobutanoic acid methyl ester hydrochloride; L-2-Amino-2-methylbutyric acid methyl ester HCl; Methyl α-aminoisovalerate hydrochloride (related); 2-Amino-2-methylbutyric acid methyl ester HCl; AMBE hydrochloride; Methyl 2-amino-2-methylbutyrate hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-Methyl-Butyric Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product quality. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.