Description

Brevican is a chondroitin sulfate proteoglycan that plays a crucial structural and regulatory role in the central nervous system. This high-purity compound is essential for advanced research in neurobiology and the development of novel therapeutic strategies. It is primarily utilized by researchers and developers in the fields of neuroscience, regenerative medicine, and pharmaceutical discovery, particularly for studying extracellular matrix dynamics and neural repair mechanisms.

Application

• Neuroscience Research: Fundamental studies on brain extracellular matrix composition, neural plasticity, and cell signaling pathways.
• Biomaterial Development: Serves as a key component in designing scaffolds for neural tissue engineering and regenerative applications.
• Drug Discovery & Target Validation: Used in assays to identify and validate novel targets for neurological disorders and brain cancers.
• Biochemical Standard: Acts as a reference standard in analytical methods for proteoglycan characterization and quantification.
• Cell Culture & In Vitro Models: Incorporated into specialized matrices to support the growth and differentiation of neural cell types.

Basic Information

Product Name	Brevican
CAS No.	155981-63-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Brevican core protein; Brain-enriched hyaluronan-binding protein; BEHAB; Chondroitin sulfate proteoglycan 4; CSPG4 (in part); Aggrecan family member; PG-CAN; BCAN
EINECS	Contact for details

Quality Control

Our Brevican is produced and handled under stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and biological activity are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For extended storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to reference standard
Purity (SDS-PAGE)	≥ 90%
Protein Content	≥ 85% (Biuret or similar)
Endotoxin Level	< 1.0 EU/mg (LAL test)
Biological Activity	Assessed by functional binding assay
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.