Description

1-[2-(Maleimido)Ethyl]-4-[5-(4-Methoxyphenyl)-2-Oxazolyl]Pyridinium Triflate is a specialized heterocyclic organic salt designed for advanced chemical synthesis and bioconjugation. This compound is valued for its dual functionality, combining a reactive maleimide group for thiol-specific coupling with a photoactive oxazolylpyridinium moiety. It is primarily utilized by researchers and process chemists in the pharmaceutical and biotechnology sectors for developing targeted drug delivery systems, photoaffinity labeling probes, and advanced polymer materials.

Application

• Photoaffinity Labeling (PAL): A critical reagent for mapping biomolecular interaction sites and identifying drug targets due to its photo-reactive oxazolylpyridinium group.
• Bioconjugation & Linker Chemistry: The maleimide functionality enables stable, site-specific conjugation to thiol groups (-SH) on proteins, peptides, and antibodies for creating antibody-drug conjugates (ADCs) and diagnostic probes.
• Polymer & Material Science: Serves as a cross-linking agent or functional monomer for synthesizing smart polymers, hydrogels, and surface-modified materials with light-responsive properties.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic agents, particularly in oncology and targeted therapies.
• Chemical Biology Probes: Employed to create activity-based probes for studying enzyme function and cellular pathways.

Basic Information

Product Name	1-[2-(Maleimido)Ethyl]-4-[5-(4-Methoxyphenyl)-2-Oxazolyl]Pyridinium Triflate
CAS No.	155862-98-9
Molecular Formula	C22H20F3N3O6S
Molecular Weight	511.47 g/mol
Synonyms	4-[5-(4-Methoxyphenyl)-1,3-oxazol-2-yl]-1-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]pyridinium trifluoromethanesulfonate; 1-[2-(Maleimido)ethyl]-4-[5-(4-methoxyphenyl)-2-oxazolyl]pyridinium trifluoromethanesulfonate; Maleimide-Oxazolylpyridinium Triflate; Photo-reactive Maleimide Reagent; PAL Maleimide Crosslinker
EINECS	Contact for details

Quality Control

Our production of 1-[2-(Maleimido)Ethyl]-4-[5-(4-Methoxyphenyl)-2-Oxazolyl]Pyridinium Triflate adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere when not in use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.